How is mouth bacteria involved in brain clot?

A group of researchers from Finland’s Tampere University have researched 75 people by taking the clot samples of patients who were under emergency treatment for ischemic stroke, who were admitted to Tampere University Hospital’s Acute Stroke Unit.

The patients under treatment have undergone thrombectomies that are it is a procedure where the blood clot is removed through catheters conducted via arteries. The catheters can be positioned in such a way that the stent retrievers and aspirations can help in reducing or eliminating the clot.

When the researchers further reviewed their collected data, they found that 79% of them have had DNA from oral bacteria. Most of the bacteria were Streptococcus minis type that belongs to a class of what the scientists call as viridans streptococci.

The outcome of their review was the level of oral bacteria found in the blood clot samples was much higher as compared to other samples taken by the surgeons from the same patients.

The team of researchers noted their findings in the Journal of the American Heart Association study. The Journal has depictions of what the researchers have found in all the while. As a part of the investigation, the Tampere university had taken over ten years to figure out the role of bacteria in cardiovascular disease.

The investigation further throws light on the blood clots that have caused heart attacks, an aneurysm in the brain, causing thrombosis in legs arteries and veins. It has also cited that these bacteria have created a type of heart infection known as endocarditis.

When a stroke occurs, the brain experiences a sudden disruption in its supply of blood. The cells that produce oxygen and nutrients can cause damage to tissues and loss of brain functioning. The ischemic stroke is the most common type of stroke that occurs when the blood supply to an artery that feeds the brain is reduced due to a blood clot.

According to the World Stroke Organisation, one out of six people in the world experience a stroke in their lifetime. The cause of the stroke is a condition in which the plaques form a wall over the arteries that narrows and gardens over time. This condition is known as atherosclerosis. These plaques are deposits of cholesterol, fat, cellular waste and other materials.

Despite the origin of these plaques, atherosclerosis can increase the rate of heart disease, angina, carotid artery disease as well as peripheral disease of the artery. It may so happen that plates might leave some of its residues into the bloodstream that can affect an artery that supplies blood to the brain, and as a result, an ischemic stroke occurs.

In a nutshell, the researchers cited the streptococci bacteria in the mouth cause severe infection as they enter the blood circulation phase. It is also found out that these bacteria can activate the blood platelets directly. However, activated platelets can trigger in speeding up the development of atherothrombotic lesions. It is also unclear whether oral bacteria can cause a stroke, or it is the role of bystanders. Further, it was discussed that regular dental care should be taken for the prevention of ischemic stroke.

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Josh Mick

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